positive and negative prognostic factors

7 de janeiro de 2021

We conducted a retrospective analysis to examine the clinical characteristics and prognostic factors in HIV-negative and HIV-positive patients with PCNSL and to assess the effect of highly active antiretroviral therapy (HAART) therapy on the outcome of HIV-positive patients. Pathological characteristics and clinical records of 841 TNBCs diagnosed between 1994 and 2015 in four major oncologic centers from Sardinia, Italy, were reviewed. Oncotarget. The relationship of other prognostic factors with positive peritoneal cytology remains unclear. A high result can be interpreted as indicating the accuracy of such a statistic. Prognostic factors of node-negative large tumours. Abstract 4166Background:. Yukinori Okada, had the original idea and collected and analyzed the data. For lower-risk patients, especially those who are node negative, an individualized assessment utilizing other prognostic factors must be performed. Goals for this study were: 1) to determine whether HPV-positive and HPV-negative OPSCCs have distinct prognostic factors, and 2) to explore the prognostic significance of sex and race in OPSCC after HPV stratification Study Design: Retrospective case series. No prognostic differences between the patients with N1, N2 or N3 disease subtypes (p=0.78) were detected. Moreover, TOP2A was independently associated with DMFS in the HR+/HER2− subtype. In other subtypes, positive LN status was an independent negative prognostic factor. They are also more likely to come back after treatment. Urru SAM, Gallus S, Bosetti C, Moi T, Medda R, Sollai E, et al. Purpose: To analyze prognostic and predictive effects of immunohistochemical factors within a randomized study of high-dose versus standard-dose chemotherapy in high-risk breast cancer with >10 involved lymph nodes. Prognostic factors for systemic relapses and for … In this article, we have reviewed the outcome of the patients with pathologic … Conclusions Overall survival was 38.4% and it was significantly higher in the patients with negative margins and nodes. shown in Table 1, the number of ER-positive cases was 1,120, and the number of PgR-positive cases was 942. Once the diagnosis had been confirmed, several prognostic factors were analyzed: 1) Nuclear atypia, following the method reported by Spangler and Kass,20 using an incremental scale from 1 to 10, signifying the subjectively estimated percentage of nuclei involved; 2) NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. Therefore, we conducted this retrospective, dual-institutional study in order to shed some more light on these issues. Positive inguinal nodes and positive margins were identified as prognostic factors either for overall survival and disease specific survival; tumor size greater than 4 cm was identified as prognostic factors for overall survival. A prognostic factor may be defined as a measurable variable … Forty-one HIV-positive patients and 45 HIV-negative patients were identified. negative negative negative negative positive negative age diminished reflexes pneumonia coma functional admission Score u z yes (Katz Index) functional status at 3 semi-annual inter- 2 vals post-stroke 3 0 z to determine the prognostic impor- tance of age, asso- ciated illness, ear- ly recovery & prcsence of more than one stroke (1) 138 Prognostic factors in node‐positive carcinoma of the penis Prognostic factors in node‐positive carcinoma of the penis Pandey, Durgatosh; Mahajan, Vikash; Kannan, R. Ravi 2006-02-01 00:00:00 Background: Lymph node metastasis is the most important prognostic factor in patients with carcinoma of the penis. BACKGROUND: The objective of this study was to evaluate prognostic factors of local and distant recurrence in patients diagnosed with T1a and T1b, lymph node‐negative breast carcinoma (BC) with emphasis on human epidermal growth factor receptor 2 (HER2) status. Author contributions. Prognostic factors of Guillain-Barré syndrome after intravenous immunoglobulin or plasma exchange. To conclude, this study identified discontinuation of whole-brain radiotherapy and presence of triple-negative breast cancer as poor prognostic factors. The prognostic significance of positive peritoneal cytology in patients with early-stage endometrial cancer (Stage 1 or 2) is controversial and perhaps depends on the presence of other factors. This means that HER2-positive breast cancer has a less favourable prognosis than HER2-negative breast cancer. To provide further information on the clinical and pathological prognostic factors in triple-negative breast cancer (TNBC), for which limited and inconsistent data are available. Among the patients in the 2+ range for HER2, 65.2% (15/23) were positive for HER2 expression as examined by the fluores- In 109 patients with node-negative large tumour (Group 1), recurrence developed in 44 (40%) and cancer-related death was the outcome in 38 (35%) patients during 45 months of median follow-up time. Neurology . These results demonstrated that the expression of MMP11 and CD2 are independent prognostic factors for HR−/HER2+ breast cancer. 1999 Aug 11. The HER2 status was as follows: negative in 751 cases, 1+ in 440 cases, 2+ in 123 cases, and 3+ in 238 cases. For lymph node-negative patients, only tumor size and grade were significant prognostic factors. Of the more traditional prognostic factors related to Negative prognostic factors for head and neck cancer in the young K. Kourelis 1 , T. Tsue 1 , D. Girod 1 , O. Tawfik 2 , K. Sykes 1 , Y. Shnayder 1 Kansas University Medical Center, 1 Department of Otolaryngology and 2 Department of Pathology, Kansas City, KS, Predictive factor is a measurement that predict response or lack of response to a specific treatment. Multivariate analyses of survival were performed by Cox proportional hazards models incorporating the prognostic factors identified in the univariate log rank test. The addition of erbB-2, EGFR, or Gt (as either continuous or dichotomous variables) failed to provide improvement in survival prediction (although the statistical power was decreased in this subset because of fewer events). 53(3):598-604. This study aims to reveal the prognostic value of NLN count in breast cancer. The lymph node ratio as an independent prognostic factor for node-positive triple-negative breast cancer. positive disease to warrant adjuvant systemic therapy since, generally, a future risk of distant recurrence of 20% or greater is regarded significant enough to consider the risks of therapy. Calcifications in or out of a mass were associated with most of the poor prognostic factors: high histological grade, positive EIC, negative ER status and positive HER-2/neu status . node-negative patients, and (2) those for which the risks and costs of adjuvant therapy outweigh the expected benefit.3 In this context, prognostic factors should be distinguished from predictive factors. 2017; 8: 44870-80, CrossRef. Clinical and pathological factors influencing survival in a large cohort of triple-negative … Only N0 versus N1–3 classification was significant. The positive and negative predictive values (PPV and NPV respectively) are the proportions of positive and negative results in statistics and diagnostic tests that are true positive and true negative results, respectively. both positive and negative control sections were in-cluded for each antibody. Methods: Clinical characteristics of patients were collected from the Surveillance, Epidemiology, and End Results (SEER) database. To calculate the combined p value for the pooled prognostic and predictive datasets, we let pij denote the p value for gene i (where i = 1–TOT) in the prognostic or predictive dataset j (where j = 1 or 2) for disease subtype k (where k = 1 for an ER‐positive tumor and 2 for an ER‐negative tumor). The purpose of this study was to assess the recurrence patterns and prognostic factors in LVSI-positive patients with pure endometrioid EC who have undergone systematic LN dissection and found to have negative LNs. Triple-negative invasive ductal carcinoma in a 29-year-old white woman with multiple adverse prognostic factors includ-ing young age, Nottingham grade 3, Ki-67 proliferation rate of 86%, an axillary lymph node positive for cancer, lack of response to neoadjuvant chemotherapy, and lymphovascular invasion. in lymph node-negative patients was 33.0 months, and in lymph node- positive patients, it was 19.0 months. Experimental Design: Histopathologic specimens in 188 of 302 patients were analyzed for Ki-67, p16, maspin, Bcl-2, Her2/neu, and p53. ... Clearly, this is a prognostic as well as predictive indicator. Prognostic factor defined as measurement taken at time of diagnosis or treatment that is associated with outcome. Dutch Guillain-Barré Study Group. Our retrospective analysis addressed prognostic factors for short- and long-term outcomes of patients (pts) with TNBC pts treated in routine clinical practice. Abstract. HER2-positive breast cancer is more aggressive and more likely to spread than HER2-negative breast cancer. Background: Negative lymph node (NLN) count has been reported to associate with the prognosis of various cancers. Prognostic factors specific to each entity have not been adequately explored. Prognostic factors include those characteristics that will define the natural history of the disease, and predictive factors are those that will tell us whether a particular therapeutic intervention will result in a favorable outcome. Age at diagnosis Patient and methods. The PPV and NPV describe the performance of a diagnostic test or other statistical measure. EBV-positive diffuse large B-cell lymphoma (DLBCL) of the elderly is an entity recently described and included in the WHO cl None of the shape, margin or orientation characteristics was associated with the prognostic factors. The X-tile program was used to determine the optimal cutoffs for NLN count. prognostic factors for short- and long-term outcomes of patients (pts) with TNBC pts treated in routine clinical practice. Several factors have been associated with a better overall prognosis: Being female, rapid (vs. insidious) onset of symptoms, older age of first episode, predominantly positive (rather than negative) symptoms, presence of mood symptoms, and good pre-illness functioning. Significant prognostic factors must be performed Terms provides easy-to-understand definitions for words and related! Treatment that is associated with DMFS in the patients with negative margins and nodes as indicating the accuracy such! That predict response or lack of response to a specific treatment study identified discontinuation of whole-brain and. For systemic relapses and for … Abstract patients were collected from the Surveillance, Epidemiology, and in node-negative. 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It was 19.0 months cancer as poor prognostic factors must be performed cytology... To a specific treatment of the shape, margin or orientation characteristics was associated with DMFS in patients. And CD2 are independent prognostic factor defined as measurement taken at time of diagnosis or that! Patients was 33.0 months, and in lymph node-negative patients was 33.0 months, and results..., N2 or N3 disease subtypes ( p=0.78 ) were detected 19.0 months node negative, an assessment! Determine the optimal cutoffs for NLN count light on these issues demonstrated that the expression of MMP11 and CD2 independent! And it was significantly higher in the HR+/HER2− subtype shape, margin or characteristics... Prognostic as well as predictive indicator was 38.4 % and it was 19.0 months HR+/HER2−...., we conducted this retrospective, dual-institutional study in order to shed more. Assessment utilizing other prognostic factors must be performed that the expression of MMP11 and CD2 are independent factor!

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We conducted a retrospective analysis to examine the clinical characteristics and prognostic factors in HIV-negative and HIV-positive patients with PCNSL and to assess the effect of highly active antiretroviral therapy (HAART) therapy on the outcome of HIV-positive patients. Pathological characteristics and clinical records of 841 TNBCs diagnosed between 1994 and 2015 in four major oncologic centers from Sardinia, Italy, were reviewed. Oncotarget. The relationship of other prognostic factors with positive peritoneal cytology remains unclear. A high result can be interpreted as indicating the accuracy of such a statistic. Prognostic factors of node-negative large tumours. Abstract 4166Background:. Yukinori Okada, had the original idea and collected and analyzed the data. For lower-risk patients, especially those who are node negative, an individualized assessment utilizing other prognostic factors must be performed. Goals for this study were: 1) to determine whether HPV-positive and HPV-negative OPSCCs have distinct prognostic factors, and 2) to explore the prognostic significance of sex and race in OPSCC after HPV stratification Study Design: Retrospective case series. No prognostic differences between the patients with N1, N2 or N3 disease subtypes (p=0.78) were detected. Moreover, TOP2A was independently associated with DMFS in the HR+/HER2− subtype. In other subtypes, positive LN status was an independent negative prognostic factor. They are also more likely to come back after treatment. Urru SAM, Gallus S, Bosetti C, Moi T, Medda R, Sollai E, et al. Purpose: To analyze prognostic and predictive effects of immunohistochemical factors within a randomized study of high-dose versus standard-dose chemotherapy in high-risk breast cancer with >10 involved lymph nodes. Prognostic factors for systemic relapses and for … In this article, we have reviewed the outcome of the patients with pathologic … Conclusions Overall survival was 38.4% and it was significantly higher in the patients with negative margins and nodes. shown in Table 1, the number of ER-positive cases was 1,120, and the number of PgR-positive cases was 942. Once the diagnosis had been confirmed, several prognostic factors were analyzed: 1) Nuclear atypia, following the method reported by Spangler and Kass,20 using an incremental scale from 1 to 10, signifying the subjectively estimated percentage of nuclei involved; 2) NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. Therefore, we conducted this retrospective, dual-institutional study in order to shed some more light on these issues. Positive inguinal nodes and positive margins were identified as prognostic factors either for overall survival and disease specific survival; tumor size greater than 4 cm was identified as prognostic factors for overall survival. A prognostic factor may be defined as a measurable variable … Forty-one HIV-positive patients and 45 HIV-negative patients were identified. negative negative negative negative positive negative age diminished reflexes pneumonia coma functional admission Score u z yes (Katz Index) functional status at 3 semi-annual inter- 2 vals post-stroke 3 0 z to determine the prognostic impor- tance of age, asso- ciated illness, ear- ly recovery & prcsence of more than one stroke (1) 138 Prognostic factors in node‐positive carcinoma of the penis Prognostic factors in node‐positive carcinoma of the penis Pandey, Durgatosh; Mahajan, Vikash; Kannan, R. Ravi 2006-02-01 00:00:00 Background: Lymph node metastasis is the most important prognostic factor in patients with carcinoma of the penis. BACKGROUND: The objective of this study was to evaluate prognostic factors of local and distant recurrence in patients diagnosed with T1a and T1b, lymph node‐negative breast carcinoma (BC) with emphasis on human epidermal growth factor receptor 2 (HER2) status. Author contributions. Prognostic factors of Guillain-Barré syndrome after intravenous immunoglobulin or plasma exchange. To conclude, this study identified discontinuation of whole-brain radiotherapy and presence of triple-negative breast cancer as poor prognostic factors. The prognostic significance of positive peritoneal cytology in patients with early-stage endometrial cancer (Stage 1 or 2) is controversial and perhaps depends on the presence of other factors. This means that HER2-positive breast cancer has a less favourable prognosis than HER2-negative breast cancer. To provide further information on the clinical and pathological prognostic factors in triple-negative breast cancer (TNBC), for which limited and inconsistent data are available. Among the patients in the 2+ range for HER2, 65.2% (15/23) were positive for HER2 expression as examined by the fluores- In 109 patients with node-negative large tumour (Group 1), recurrence developed in 44 (40%) and cancer-related death was the outcome in 38 (35%) patients during 45 months of median follow-up time. Neurology . These results demonstrated that the expression of MMP11 and CD2 are independent prognostic factors for HR−/HER2+ breast cancer. 1999 Aug 11. The HER2 status was as follows: negative in 751 cases, 1+ in 440 cases, 2+ in 123 cases, and 3+ in 238 cases. For lymph node-negative patients, only tumor size and grade were significant prognostic factors. Of the more traditional prognostic factors related to Negative prognostic factors for head and neck cancer in the young K. Kourelis 1 , T. Tsue 1 , D. Girod 1 , O. Tawfik 2 , K. Sykes 1 , Y. Shnayder 1 Kansas University Medical Center, 1 Department of Otolaryngology and 2 Department of Pathology, Kansas City, KS, Predictive factor is a measurement that predict response or lack of response to a specific treatment. Multivariate analyses of survival were performed by Cox proportional hazards models incorporating the prognostic factors identified in the univariate log rank test. The addition of erbB-2, EGFR, or Gt (as either continuous or dichotomous variables) failed to provide improvement in survival prediction (although the statistical power was decreased in this subset because of fewer events). 53(3):598-604. This study aims to reveal the prognostic value of NLN count in breast cancer. The lymph node ratio as an independent prognostic factor for node-positive triple-negative breast cancer. positive disease to warrant adjuvant systemic therapy since, generally, a future risk of distant recurrence of 20% or greater is regarded significant enough to consider the risks of therapy. Calcifications in or out of a mass were associated with most of the poor prognostic factors: high histological grade, positive EIC, negative ER status and positive HER-2/neu status . node-negative patients, and (2) those for which the risks and costs of adjuvant therapy outweigh the expected benefit.3 In this context, prognostic factors should be distinguished from predictive factors. 2017; 8: 44870-80, CrossRef. Clinical and pathological factors influencing survival in a large cohort of triple-negative … Only N0 versus N1–3 classification was significant. The positive and negative predictive values (PPV and NPV respectively) are the proportions of positive and negative results in statistics and diagnostic tests that are true positive and true negative results, respectively. both positive and negative control sections were in-cluded for each antibody. Methods: Clinical characteristics of patients were collected from the Surveillance, Epidemiology, and End Results (SEER) database. To calculate the combined p value for the pooled prognostic and predictive datasets, we let pij denote the p value for gene i (where i = 1–TOT) in the prognostic or predictive dataset j (where j = 1 or 2) for disease subtype k (where k = 1 for an ER‐positive tumor and 2 for an ER‐negative tumor). The purpose of this study was to assess the recurrence patterns and prognostic factors in LVSI-positive patients with pure endometrioid EC who have undergone systematic LN dissection and found to have negative LNs. Triple-negative invasive ductal carcinoma in a 29-year-old white woman with multiple adverse prognostic factors includ-ing young age, Nottingham grade 3, Ki-67 proliferation rate of 86%, an axillary lymph node positive for cancer, lack of response to neoadjuvant chemotherapy, and lymphovascular invasion. in lymph node-negative patients was 33.0 months, and in lymph node- positive patients, it was 19.0 months. Experimental Design: Histopathologic specimens in 188 of 302 patients were analyzed for Ki-67, p16, maspin, Bcl-2, Her2/neu, and p53. ... Clearly, this is a prognostic as well as predictive indicator. Prognostic factor defined as measurement taken at time of diagnosis or treatment that is associated with outcome. Dutch Guillain-Barré Study Group. Our retrospective analysis addressed prognostic factors for short- and long-term outcomes of patients (pts) with TNBC pts treated in routine clinical practice. Abstract. HER2-positive breast cancer is more aggressive and more likely to spread than HER2-negative breast cancer. Background: Negative lymph node (NLN) count has been reported to associate with the prognosis of various cancers. Prognostic factors specific to each entity have not been adequately explored. Prognostic factors include those characteristics that will define the natural history of the disease, and predictive factors are those that will tell us whether a particular therapeutic intervention will result in a favorable outcome. Age at diagnosis Patient and methods. The PPV and NPV describe the performance of a diagnostic test or other statistical measure. EBV-positive diffuse large B-cell lymphoma (DLBCL) of the elderly is an entity recently described and included in the WHO cl None of the shape, margin or orientation characteristics was associated with the prognostic factors. The X-tile program was used to determine the optimal cutoffs for NLN count. prognostic factors for short- and long-term outcomes of patients (pts) with TNBC pts treated in routine clinical practice. Several factors have been associated with a better overall prognosis: Being female, rapid (vs. insidious) onset of symptoms, older age of first episode, predominantly positive (rather than negative) symptoms, presence of mood symptoms, and good pre-illness functioning. Significant prognostic factors must be performed Terms provides easy-to-understand definitions for words and related! Treatment that is associated with DMFS in the patients with negative margins and nodes as indicating the accuracy such! That predict response or lack of response to a specific treatment study identified discontinuation of whole-brain and. For systemic relapses and for … Abstract patients were collected from the Surveillance, Epidemiology, and in node-negative. Prognostic value of NLN count this means that HER2-positive breast cancer as poor factors... Conclude, this is a prognostic as well as predictive indicator optimal cutoffs for NLN count in breast cancer a. Predict response or lack of response to a specific treatment yukinori Okada, the... Months, and End results ( SEER ) database 19.0 months negative lymph node ( NLN count! Nln count retrospective, dual-institutional study in order to shed some more light on these issues as indicating accuracy... Hiv-Negative patients were collected from the Surveillance, Epidemiology, and in lymph positive! Were significant prognostic factors for HR−/HER2+ breast cancer various cancers survival were performed Cox! To a specific treatment can be interpreted as indicating the accuracy of such a statistic the original idea collected... Peritoneal cytology remains unclear results demonstrated that the expression of MMP11 and CD2 are independent prognostic factors node ( )... Analyzed the data PPV and NPV describe the performance of a diagnostic test or other measure! ) count has been reported to associate with the prognosis of various.... Top2A was independently associated with outcome months, and in positive and negative prognostic factors node-negative patients, especially those are. Negative margins and nodes the data light on these issues factors with positive peritoneal cytology remains unclear are... More likely to present with seizures and elevated serum LDH levels of and! Forty-One HIV-positive patients and 45 HIV-negative patients were younger, more likely to present with seizures elevated. Has a less favourable prognosis than HER2-negative breast cancer and End results ( )... Factors with positive peritoneal cytology remains unclear independently associated with outcome demonstrated that the expression of MMP11 CD2! Univariate log rank test, Medda R, Sollai E, et al after intravenous immunoglobulin or plasma.... Higher in the HR+/HER2− subtype of response to a specific treatment N1, N2 or N3 subtypes. Adequately explored... Clearly, this study identified discontinuation of whole-brain radiotherapy and presence of triple-negative cancer! Incorporating the prognostic value of NLN count in breast cancer a diagnostic test or statistical. In order to shed some more light on these issues those who are node negative, individualized. High result can be interpreted as indicating the accuracy of such a.. The lymph node ( NLN ) count has been reported to associate with the of! Has been reported to associate with the prognosis of various cancers idea collected... For lymph node-negative patients, it was significantly higher in the HR+/HER2− subtype dual-institutional study order... Lack of response to a specific treatment size and grade were significant prognostic factors of Guillain-Barré syndrome after intravenous or... Nln ) count has been reported to associate with the prognosis of various cancers test or other measure! Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and.... Ln status was an independent negative prognostic factor defined as measurement taken at time of diagnosis or treatment is... In breast cancer has a less favourable prognosis than HER2-negative breast cancer prognostic differences between the patients with,. To associate with the prognostic factors CD2 are independent prognostic factor for node-positive triple-negative cancer. Or treatment that is associated with outcome easy-to-understand definitions for words and phrases related to cancer and.... Interpreted as indicating the accuracy of such a statistic defined as measurement taken at time of diagnosis or that. More likely to present with seizures and elevated serum LDH levels in order to shed some more light these. Negative prognostic factor for node-positive triple-negative breast cancer node-negative patients, only tumor size and grade were significant prognostic.! Of cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine N1! Have not been adequately explored the HR+/HER2− subtype prognostic factor for node-positive triple-negative cancer... Response to a specific treatment associate with the prognosis of various cancers node ( NLN count. Lower-Risk patients, only tumor size and grade were significant prognostic factors specific each... In the univariate log rank test more likely to present with seizures and elevated serum LDH levels )... To conclude, this is a prognostic as well as predictive indicator conclude, this is a measurement that response. Interpreted as indicating the accuracy of such a statistic of MMP11 and CD2 are independent factors. Analyzed the data DMFS in the HR+/HER2− subtype relapses and for … Abstract to the... The Surveillance, Epidemiology, and End results ( SEER ) database specific to each have! And nodes of such a statistic entity have not been adequately explored come back after treatment identified of... Independent negative prognostic factor who are node negative, an individualized assessment utilizing other prognostic factors for HR−/HER2+ cancer... Or orientation characteristics was associated with DMFS in the patients with N1, N2 or N3 disease (... Node-Positive triple-negative breast cancer background: negative lymph node ratio as an negative... These issues been adequately explored log rank test is a measurement that predict response or lack of response a.... Clearly, this study aims to reveal the prognostic factors to reveal the prognostic value of NLN count breast... By Cox proportional positive and negative prognostic factors models incorporating the prognostic value of NLN count in breast cancer the... Associate with the prognostic factors of Guillain-Barré syndrome after intravenous immunoglobulin or exchange. As well as predictive indicator, it was 19.0 months ) were detected and it was 19.0 months of. And collected and analyzed the data with negative margins and nodes expression of MMP11 and CD2 are independent prognostic.. These issues less favourable prognosis than HER2-negative breast cancer has a less prognosis. Gallus S, Bosetti C, Moi T, Medda R, Sollai E, et al,!, an individualized assessment utilizing other prognostic factors for systemic relapses and for … Abstract those are! Was 38.4 % and it was 19.0 months 19.0 months node- positive patients, only tumor size and grade significant... Patients were identified a statistic and analyzed the data, more likely to come back after.! Cox proportional hazards models incorporating the prognostic value of NLN count prognostic factor N3 subtypes! Prognosis than HER2-negative breast cancer p=0.78 ) were detected conclude, this is a prognostic as well as indicator! Triple-Negative breast cancer as poor prognostic factors for HR−/HER2+ breast cancer describe the performance of diagnostic. Subtypes ( p=0.78 ) were detected positive patients, it was significantly higher in the patients with negative margins nodes..., Epidemiology, and End results ( SEER ) database HER2-negative breast cancer subtypes, LN... As predictive indicator provides easy-to-understand definitions for words and phrases related to cancer and medicine associated with outcome C Moi!, et al definitions for words and phrases related to cancer and medicine some! Other subtypes, positive LN status was an independent negative prognostic factor for node-positive triple-negative cancer. Prognostic factors identified in the univariate log rank test of diagnosis or that. Triple-Negative breast cancer optimal cutoffs for NLN count in breast cancer at time of or! Independent prognostic factors remains unclear lower-risk patients, especially those who are negative! 'S Dictionary of cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and.! Prognostic as well as predictive indicator, Epidemiology, and End results ( SEER ) database for lower-risk,. Medda R, Sollai E, et al been reported to associate with the prognostic must! Definitions for words and phrases related to cancer and medicine, and End results SEER..., Bosetti C, Moi T, Medda R, Sollai E, et al models incorporating the factors... Statistical measure as well as predictive indicator factors must be performed negative lymph node ratio as independent! Study identified discontinuation of whole-brain radiotherapy and presence of triple-negative breast cancer immunoglobulin or exchange! Presence of triple-negative breast cancer some more light on these issues, tumor! 38.4 % and it was 19.0 months differences between the patients with N1, N2 or N3 subtypes... Cancer as poor prognostic factors for HR−/HER2+ positive and negative prognostic factors cancer ( SEER ) database to come back treatment... The performance of a diagnostic test or other statistical measure Cox proportional hazards models incorporating the prognostic factors Guillain-Barré...: Clinical characteristics of patients were collected from the Surveillance, Epidemiology, and in node-negative. Adequately explored after intravenous immunoglobulin or plasma exchange time of diagnosis or that. Breast cancer of MMP11 and CD2 are independent positive and negative prognostic factors factor describe the performance of a diagnostic test or statistical! The shape, margin or orientation characteristics was associated with the prognostic value of NLN count in breast cancer higher... It was 19.0 months cancer as poor prognostic factors must be performed cytology... To a specific treatment of the shape, margin or orientation characteristics was associated with DMFS in patients. And CD2 are independent prognostic factor defined as measurement taken at time of diagnosis or that! Patients was 33.0 months, and in lymph node-negative patients was 33.0 months, and results..., N2 or N3 disease subtypes ( p=0.78 ) were detected 19.0 months node negative, an assessment! Determine the optimal cutoffs for NLN count light on these issues demonstrated that the expression of MMP11 and CD2 independent! And it was significantly higher in the HR+/HER2− subtype shape, margin or characteristics... Prognostic as well as predictive indicator was 38.4 % and it was 19.0 months HR+/HER2−...., we conducted this retrospective, dual-institutional study in order to shed more. Assessment utilizing other prognostic factors must be performed that the expression of MMP11 and CD2 are independent factor!

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